Effects of Fluid Loading with Water, Normal Saline, Coffee and Coke on Urinary Output, pH and Specific Gravity in Young Healthy Undergraduate Students

Obehi E. Ebo*, Chinyem N.  Ighodaro, Wisdom J. Silas
Department of Physiology, College of Basic Medical Sciences, University of Benin, Edo State, Nigeria.
Corresponding Author: emmanuella.okojie@uniben.edu; Tel: +2347035522957
Recieved Date: May 19, 2019; Accepted Date: July 26, 2020; Published Date: 27 July 2020
Citation: Ebo OE, Ighodaro CN, Silas WJ. Effects of Fluid Loading with Water, Normal Saline, Coffee and Coke on Urinary Output, pH and Specific Gravity in Young Healthy Undergraduate Students.  Trop J Nat Prod Res. 2020; 4(7):319-321.  https://doi.org/10.26538/tjnpr/v4i7.12
Copyright: © 2020 Ebo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ABSTRACT

Balance of water and electrolyte is an important homeostatic function of the kidneys. Their excretion depends on various factors such as, state of hydration, plasma osmolarity, etc. There are rare reports on diuretic effect of Coffee and Coke on some urinary parameters. Hence, the study is aimed at investigating the effect of Water, Normal Saline, Coffee and Coke in young healthy undergraduate students. A total of forty (40) randomly selected, healthy undergraduate students were recruited for this study. They were randomly divided into four groups. One liter (1 L) of Water, Normal Saline, Coffee and Coke were administered on different days to the same subjects. The subjects were made to void their bladders before ingesting these substances and the urine samples collected were taken as control sample at the time zero (T = 0). Thereafter, all the subjects emptied their bladders and their urine was collected at 30 minutes interval for 150 minutes. The urinary output, pH and specific gravity were determined. The results showed that urine output for Water, Coffee and Coke produced diuresis while Normal Saline did not. The reductions in specific gravity and pH of urine also accompanied these diuretic effects.

Keywords: Fluid loading, Homeostatic function, Diuresis, Coffee, Coke.
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