GC-MS Analysis of n-Hexane Fruit Peel Extract of Persea americana (Lauraceae)

Obinna P. Okezu1, Umar T. Mamza2*, Samuel N. Adawara2 
1Department of Pharmaceutical Chemistry, University of Lagos, Nigeria.
2Department of Pure and Applied Chemistry, University of Maiduguri, Nigeria.

Corresponding Author: drutmamza_2587@yahoo.com; Tel: +2348026923506
Recieved Date: March 22, 2020; Accepted Date: April 22, 2020; Published Date: 30 April 2020
Citation: Citation: Okezu OP, Mamza UT, Adawara SN. GC-MS Analysis of n-Hexane Fruit Peel Extract of Persea americana (Lauraceae). Trop J Nat Prod Res. 2020; 4(4):146-152.  https://doi.org/10.26538/tjnpr/v4i4.6
Copyright: © 2020 Okezu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Persea americana belongs to the family of Lauraceae and it is well known in Nigerian traditional medicine for its traditional uses. The present investigation was carried out to determine the possible bioactive components of n-hexane extract of P. americana fruit peel using GC-MS analysis.  Fifteen (15) components from P. americana fruit peel were identified.  The prominent components in the n-Hexane extract of the fruit peel were caryophyllene,1H-cyclopropa[a] naphthalene, 2,3,5-trimethyl-1,4-benzenediol, caryophyllene oxide, dibutylphthalate, n-hexadecanoic acid, oleic acid, cis-13-octadecen-1-yl-acetate, dodecane-2,6,11-trimethyl,Bis(2-ethylhexyl)phthaltate,(1R,3E,7E,11R)-1,5,5,8-Tetramethyl(-12-oxabicyclo[9.1.0] dodeca-3,7-diene, and (1R,9R,E)-4,11,11-trimethyl-8-methylenebicyclo[7.2.0] undec-4-ene. The presence of various bioactive compounds confirms the application of P. americana for various ailments by traditional practitioners. However, bioassay-guided isolation and characterization of the individual phytocompound should be carried out in order to find a novel drug or lead compound(s).

Keywords: GC-MS Analysis, Persea americana, Bioactive compounds, n-Hexane extract.
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