Adicardin and Other Coumarins from Breonadia salicina (Vahl) Hepper

Barnabas J. Nvau1*, Bawazeer Sami2, Olugbenga S. Ajibade3, Irvine A. Gray4, John. O. Igoli4, 5
1Department of Chemistry, Plateau State University, Bokkos, Nigeria. 
2College of Pharmacy, Umm Al-qura University, Makkah, Saudi Arabia, 
3Department of Chemical Sciences, Redeemer’s University, Ede, Osun State, Nigeria. 
4Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, G4 0RE, Glasgow UK. 
5Department of Chemistry, University of Agriculture, Makurdi, Nigeria.

Corresponding Author: p.editor.tjnpr@gmail.com; Tel: +2348035807728
Recieved Date: September 08, 2019; Accepted Date: October 18, 2019; Published Date: 29 October 2019
Citation: Nvau JB, Sami B, Ajibade OS, Gray IA, Igoli JO. Adicardin and Other Coumarins from Breonadia salicina (Vahl) Hepper. Trop J Nat Prod Res. 2019; 3(9):298-301.  https://doi.org/10.26538/tjnpr/v3i9.3
Copyright: © 2019 Nvau et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ABSTRACT

Breonadia salicina is an ethnomedicinal plant used in North Central Nigeria to treat sleeping sickness and respiratory diseases. The stem bark of the plant was extracted with methanol and the extract partitioned between dichloromethane and water. The dichloromethane soluble portion was subjected to column chromatography which resulted in the isolation of 7-(?-Dapiofuranosyl (1-6)-?-D-glucopyranosyl) umbelliferone, ?-amyrin, stigmasterol, 7- hydroxycoumarin and 6- hydroxy-7-methoxy coumarin. The structures of these compounds were elucidated based on NMR spectral analysis. This is the first report of these compounds from the plant.

Keywords: Terpenoids, Coumarins, Medicinal plant, Breonadia salicina, Adicardin
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