Aphrodisiac Potential of Methanol Root Extract of Hunteria umbellata in Male Wistar Rats

Emmanuel O. Oshomoh1* and Benjamin O. Gabriel2

1Department of Science Laboratory Technology, Fac. of Life Sciences, University of Benin, Edo State. Nigeria
2Phytomedicine Unit, Department of Plant Biology and Biotechnology, Benin City, Edo State. Nigeria

Corresponding Author: emmanuel.oshomoh@uniben.edu ; Tel: +2348055452141
Recieved Date: 04 November 2020; Accepted Date: 16 September 2021; Published Date: 4 October
Citation: Oshomoh EO and Gabriel BO. Aphrodisiac Potential of Methanol Root Extract of Hunteria umbellata in Male Wistar Rats. Trop J Nat Prod Res. 2021; 5(9):1645-1649. http://www.doi.org/10.26538/tjnpr/v5i9.19
Copyright:
© 2021 Oshomoh and Gabriel. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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ABSTRACT

Hunteria umbellata have been used locally for the treatment of low libido, obesity, diabetes mellitus, infertility, pyrexia, pain, hypertension and as immune booster. This study was aim to evaluate the aphrodisiac activity of the methanol root extract of H. umbellata in male Wistar rats.  Acute toxicity of the extract was evaluated using standard protocol. The extract at graded doses (25, 50 and 100 mg/kg) and reference drug (10 mg/kg sildenafil citrate) were orally administered for 14 days to investigate aphrodisiac property. The female animals were made receptive via artificial hormonal stimulation. The effects of H. umbellata on body and reproductive organ mass indices were determined. The aphrodisiac behaviour monitored were; Mounting Frequency (MF), Intromission Frequency (IF), Ejaculation Frequency (EF), Mounting Latency (ML), Intromission Latency (IL) and Ejaculation latency (EL). The obtained result showed no mortality or side effects from the acute toxicity study. There was a significant increase in MF, IF, EF, ML, IL and EL as well as a significant increase in serum testosterone level across the treated groups when compared with the control. In conclusion, the result of this study indicates that H. umbellata has aphrodisiac capacity that may be of great ethnomedicinal benefit since there are no adverse toxicity reports.

Keywords: Hunteria umbellata, aphrodisiac, male rat, reproductive properties
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
Index Copernicus Value (ICV) for 2017: 59.83
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