Isolation and Spectroscopic Analysis of Compounds from Baccaurea racemosa (Reinw. ex Blume) Müll. Arg. Pulp

Lina Permatasari1, Sugeng Riyanto1, Abdul Rohman1,2*
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia
2Center for Excellence, Institute of Halal Industry and Systems (PUI-PT IHIS), Universitas Gadjah Mada, Yogyakarta 55281, Indonesia


Corresponding Author: abdulkimfar@gmail.com ; Tel: +62-878-3844-5216
Recieved Date: 10 June; Accepted Date: 26 August ; Published Date: 03 September
Citation: Permatasari L, Riyanto S, Rohman A. Isolation and Spectroscopic Analysis of Compounds from Baccaurea racemosa (Reinw. ex Blume) Müll. Arg. Pulp. Trop J Nat Prod Res. 2021; 5(8):1434-1438. http://www.doi.org/10.26538/tjnpr/v5i8.18
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© 2021 Permatasari et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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ABSTRACT

The pulp of Baccaurea racemosa (Reinw. ex Blume) Müll. Arg. is reported to have active compounds with medicinal importance, such as anti-inflammatory and antioxidant activities. However, there has been no report of any isolated compounds from B. racemosa pulp. The present study aims to isolate and characterize the compounds from B. racemosa pulp and their antioxidant activity. The powdered pulp of B. racemosa was extracted using methanol and was partitioned using n-hexane, dichloromethane and ethyl acetate to get corresponding fractions. The ethyl acetate fraction was isolated using conventional column chromatography to obtain compounds 1 and 2. Based on the spectrometric analyses (1D-NMR, 2D-NMR, infrared and GC-MS), compounds 1 and 2 were identified as 5-Hydroxymethylenefurfural (5-HMF) and tartaric acid, respectively. The compound 5-HMF showed antioxidant activity with IC50 > 7.94 mM. This study is the first report related to the isolation and identification of compounds from B. racemosa pulp, therefore 5-HMF from B. racemosa may be potentially used as a candidate for natural antioxidants.

Keywords: Baccaurea racemose, Pulp, 5-Hydroxymethylenefurfural, Tartaric acid, Natural antioxidant.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
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