Evaluation of Dietary Supplementation of Pumpkin (Cucurbita pepo L) Seed on Antioxidant Status, Hormonal Level and Sexual Behavior in Male Rats

Seun F. Akomolafe1* and Ayodeji A. Olabiyi2



1Department of Biochemistry, Faculty of Science, Ekiti State University, Ado Ekiti, P.M.B 5363, Nigeria
2Department of Medical Biochemistry, Afe Babalola University, Ado Ekiti. P.M.B 5454, Nigeria

Corresponding Author: purposefulseun@yahoo.co.uk seun.akomolafe@eksu.edu.ng; Tel: +2348030460149
Recieved Date: 29 January 2021; Accepted Date: 13 May 2021; Published Date: 03 June
Citation: Akomolafe SF and Olabiyi AA. Evaluation of Dietary Supplementation of Pumpkin (Cucurbita pepo L) Seed on Antioxidant Status, Hormonal Level and Sexual Behavior in Male Rats. Trop J Nat Prod Res. 2021; 5(5):952-958. http://www.doi.org/10.26538/tjnpr/v5i5.25
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© 2021 Akomolafe and Olabiyi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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ABSTRACT

The seed of pumpkin (Cucurbita pepo L) is reportedly used as sex enhancer in folk medicine and to treat impotence in men. Despite all the documented importance of pumpkin seed in both nutrition and medicine, there is little or no scientific evidence of the sexual enhancement of seed in albino rats. In this study, sexual enhancing effect of pumpkin seed on healthy male rats was evaluated. Rats were fed with basal diets (NC), diet supplemented with raw pumpkin seed (5 and 10%), roasted pumpkin seed (5 and 10%) and sildenafil (5 mg/kg). Pre-treated of experimental rats with pumpkin seed for fourteen days led to a significant increment in antioxidant status, hormonal level and sexual behaviour. However, processed pumpkin seed appeared to be the most promising when compared to Sildenafil, a standard aphrodisiac drug. In conclusion, these behavioural, as well as biochemical parameters which revealed enhanced activities could be part of the mechanism by which the seed exerts its aphrodisiac properties.

Keywords: Aphrodisiac, Hormone, Sexual Behavior, Pumpkin Seed.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
Index Copernicus Value (ICV) for 2017: 59.83
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