Chemical and In Vitro Anti-inflammatory Assessment of Echinops erinaceus 


Shrouq H. Sweilam1,2*, Fatma M. Abdel Bar1,3, Omayma D. ElGindi2, Moshera M. El- Sherei4, Essam A. Abdel-Sattar4

1Department of Pharmacognosy, Faculty of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia
2Department of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, 11829 Cairo, Egypt 
3Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
4Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, 11562 Cairo, Egypt


Corresponding Author: shrooqsweilam@gmail.com; Tel: +9665439942295
Recieved Date: 06 March 2021; Accepted Date: 13 April 2021; Published Date: 03 May
Citation: Sweilam SH, Bar FMA, ElGindi OD, El-Sherei MM, Abdel-Sattar EA. Chemical and In Vitro Anti-inflammatory Assessment of Echinops erinaceus. Trop J Nat Prod Res. 2021; 5(4): 715-719. doi.org/10.26538/tjnpr/v5i4.20 http://www.doi.org/10.26538/tjnpr/v5i4.20
Copyright:
© 2021 Sweilam et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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ABSTRACT

Echinops erinaceus Kit Tan is a wild plant growing in the middle regions of Saudi Arabia. From the available literature, nothing has been reported on its chemical analysis or biological activity. In this study, various extracts of Echinops erinaceus were estimated for their total phenolics, and flavonoids contents. The extracts were also evaluated for their in vitro antioxidant activity using DPPH, FRAP, and ABTS assays. Furthermore, the enzyme inhibitory activity against cyclooxygenases and 15-lipoxygenase was performed. The results showed that the polar and semi-polar extracts demonstrated considerable in vitro anti-inflammatory and antioxidant activities.

Keywords: Echinops erinaceus, Asteraceae, Antioxidant, Cyclooxygenase, Lipoxygenase
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
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